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Professor

Office: 253 Kopchick Hall
Phone: 724-357-2368
Email: Avijita.Jain@iup.edu

Education

BS, Barkatullah University
MS, Tennessee Technological University
PhD, Virginia Tech
Postdoctoral Fellowship, Pacific Northwest National Laboratory

Field

Bioinorganic Chemistry
Organometallic Chemistry
Biochemistry

Courses

BIOC 481: Drug Design and Bioinorganic Chemistry
CHEM 101/102: College Chemistry I/II
CHEM 255: Biochemistry and Nutrition

Research Interests

Graph of Dr Jain's research interestsMy research interests revolve around development of electroactive and photoactive transition metal complexes with applications in photodynamic therapy and H2 production. The three research projects that I am working on are:

  • Design and development of tumor selective, peptide coupled organometallic photodynamic therapy (PDT) agents
  • Design and development of water oxidation electrocatalysts
  • Design and development of novel fluorescent sensors for monitoring protein phosphorylation

Select Publications

  1. Galan, B. R.; Reback, M. L.; Jain, A.; Apple, A. M.; Shaw W. J. Electrocatalytic Oxidation of Formate with Nickel Diphosphine Dipeptide Complexes: Effect of Ligands Modified with Amino Acids. Eur.J. Inorg. Chem. 2013 , 30, 5366-5371.
  2. Buchko, G. W.; Jain, A .; Reback, M. L.; Shaw W. J. Structural characterization of the model amphipathic peptide Ac-LKKLLKLLKKLLKL-NH2 in aqueous solution and with 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropanol. Can. J. Chem. 2013 , 91, 406-413.
  3. Reback, M. L.; Pangovska, B. G.; Ho, M. H.; Jain, A .; Squier, T. C; Raugei, S.; Roberts, J. A. S; Shaw, W. J. The role of a dipeptide outer-coordination sphere on H2-production catalysts: influence on catalytic rates and electron transfer. Inorg. Chem. 2013, 19(6), 1928-1941.
  4. Jain, A .; Buchko, G. W.; Reback, M. L.; O'Hagan M.; Pangovska, B. G.; Linehan, J. C.; Shaw W. J. Active hydrogenation catalyst with a structured, peptide-based outer-coordination sphere. ACS Catal. 2012 , 2, 2114-2118.
  5. Lense, S.; Ho, M. H.; Chen, S.; Jain, A.; Raugei, S.; Linehan J. C.; Roberts J. A. S.; Appel, A. M.; Shaw W. J. Incorporating amino acid esters into catalysts for hydrogen oxidation: steric and electronic effects and the role of water as a base. Organometallics 2012 , 31, 6719-6731.
  6. Jain, A.; Reback, M. L.; Lindstrom, M. L.; Thorgeson, C. E.; Helm, M. L.; Appel A. M.; Shaw, W. Investigating the role of the outer-coordination Sphere in [Ni(PPh2NPh-R2)2]2+ hydrogenase mimics. Inorg. Chem. 2012, 51(12), 6592-6602.
  7. Jain, A ; Helm, M. L.; Linehan, J. C.; Dubois D. L.; Shaw W. J. Biologically derived phosphino platinum complexes. Inorg. Chem. Commun. 2012 , 22, 65-67.
  8. Jain, A. ; Lense, S.; Linehan J. C.; Raugei, S.; Cho, H.; DuBois D. L.; Shaw, W. J. Incorporating peptides in the outer-coordination sphere of bioinspired electrocatalysts for hydrogen production. Inorg. Chem. 2011, 50(9), 4073-4085.
  9. Jain, A .; Wang, J. Macshaw, E.; Winkel B. S. J.; Brewer K. J. Multifunctional DNA interactions of Ru-Pt mixed metal supramolecular complexes with substituted terpyridine ligands. Inorg. Chem. 2009 , 48(19), 9077-9084.
  10. Prussin A. J.; Zhao S.; JainA .; Winkel B. S. J.; Brewer K. J DNA interaction studies of tridentate bridged Ru(II)-Pt(II) mixed-metal supramolecules. J. Inorg. Biochem. 2009, 103(3), 427- 431.
  11. Arachchige, S. M.; Brown, J. R.; Chang, E.; Jain, A .; Zigler, D. F.; Rangan, K.; Brewer, K. J. Design considerations for a system for photocatalytic hydrogen production from water employing mixed-metal photochemical molecular devices for photoinitiated electron collection. Inorg. Chem. 2008 , 48(5), 1989-2000.
  12. Jain, A.; Slebodnick, C.; Winkel, B. S. J.; Brewer, K. J. Enhanced DNA photocleavage properties of Ru(II) terpyridine complexes upon incorporation of methylphenyl substituted terpyridine and/or the polyazine bridging ligand dpp (2,3-bis(2-pyridyl)pyrazine). J.Inorg. Biochem. 2008 , 102(10), 1854-1861.
  13. Prussin, A. J., II; Zigler, D. F.; Jain, A .; Brown J. R.; Winkel, B. S. J.; Brewer, K. J. Photochemical methods to assay DNA photocleavage using supercoiled pUC18 DNA and LED or xenon arc lamp excitation. J. Inorg. Biochem . 2008 , 102(4), 731-739.
  14. Jain,A .; Winkel, B. S. J.; Brewer, K. J. J. Inorg. Biochem . 2007 , 101(10), 1525-1528.
John J. and Char Kopchick College of Natural Sciences and Mathematics
  • Madia Department of Chemistry, Biochemistry, and Physics
  • Kopchick Hall, Room 118
    421 North Walk
     Indiana, PA 15705-1076
  • Phone: 724-357-2440

Office Hours

8:00 a.m.–12:00 p.m.
1:00 p.m.–4:30 p.m.